Which agency is primarily responsible for regulating hazardous waste in the United States?

The Environmental Protection Agency (EPA) is the primary agency responsible for regulating hazardous waste in the United States. This includes overseeing the management, treatment, and disposal of hazardous waste under the Resource Conservation and Recovery Act (RCRA). The EPA establishes regulations and guidelines that ensure hazardous waste is handled in a manner that protects human health and the environment.

Through the implementation of these regulations, the EPA plays a crucial role in promoting waste minimization and encouraging recycling and recovery of materials. The agency also conducts inspections and monitors compliance among businesses that generate or handle hazardous waste, further ensuring safety and environmental protection.

Other agencies, such as OSHA, DOT, and FEMA, have relevant roles in workplace safety, transportation of hazardous materials, and emergency management, respectively. However, the comprehensive regulation and oversight of hazardous waste practices fall under the purview of the EPA, making it the correct answer in this context.