Which of the following best describes a systemic effect?

A systemic effect is characterized by its impact on the entire body rather than being localized to a specific area or organ. This term is often used in the context of how hazardous substances affect human health. When a toxic substance enters the body, it can disseminate through the bloodstream and affect multiple organ systems, leading to wide-ranging health consequences.

For example, if a chemical is ingested or absorbed, it may not only cause damage at the site of exposure but can also lead to systemic reactions that involve organs far removed from that site, resulting in symptoms that may be seen in various body systems. This broad impact underscores the importance of comprehensive protective measures and emergency response procedures in hazardous waste operations, as the effects of exposure can be far-reaching and require careful handling and monitoring.